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Ferrari R, Merli E, Cicchitelli G, Mele D, Fucili A, Ceconi C: Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review

As patients lose substantial amounts of adipose tissue, their body's natural insulation decreases, potentially making them more susceptible to environmental temperature changes

Laliberte RE, Perregaux DG, Hoth LR, Rosner PJ, Jordan CK, Peese KM, Eggler JF, Dombroski MA, Geoghegan KF, Gabel CA: Glutathione s-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing

10.1002/ptr.6155 176 RidingR

A 300mcg protocol in the clinical setting might translate to 350-400mcg in practical application to ensure adequate exposure