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Human clinical samples Urine A total of 40 urine samples from stage-II hormone receptor-negative breast cancer patients with or without smoking status (median age 59 and 56 yr) were procured from NCORP Sample Repository Facility after obtaining written informed consent from all subjects at Wake Forest Cancer Center

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7 The guidelines support the use of a combination of prescription medications and behavior counseling, such as motivational interviewing, as the gold standard of smoking-cessation treatment