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Under typical metabolic conditions, the NADP + /NADPH ratio is low

In high-cholesterol diet mice, FMO3 knockout can affect the biliary lipid secretion and slow down cholesterol absorption in the intestine (90)

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Additionally, a preclinical study using a rabbit TB model showed that bevacizumab inhibited neovascularization, enhanced drug penetration into granulomas, improved lung pathology, and increased oxygenation, suggesting its potential to enhance the effectiveness of the current TB regimens [37]

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