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5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the cytosolic enzyme that methylates nicotinamide to 1-methylnicotinamide (1-MNA) using S-adenosyl-L-methionine (SAM) as the methyl donor

[1] FDA, Warning Letters, available at: (last visited: Sep

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however, those who experience breakouts after finishing Accutane can take another short course to eliminate acne for good