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Similarly, a double blind RCT by Weissman et al 39 demonstrated no significant difference in inflammatory lesion and infiltrate count after 12 weeks of zinc supplementation, compared to placebo

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Over time, and with more decrement in thyroid hormone levels, cool and dry skin, coarse hair, loss of body hair, hoarse voice, coarse facial features, facial edema, generalized edema, bradycardia, and delayed relaxation phase of the deep tendon reflexes may be seen (8) (see Fig