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Recombinant hCG was found to be more potent than LH in both HEK293 and mouse Leydig tumour cells, demonstrating that LH and hCG display biased agonism at their shared receptor

3134 MTX can create DNA adducts upon cell entry, resulting in the production of ROS and activation of p53, 35 which is a well-known tumor suppressor gene and has been linked to MTX-induced apoptosis

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Additionally, the trials focused on specific outcomes like weight loss efficacy

Adv Energy Mater 8(25):1801289 Li XG, Guan BY, Gao SY, Lou XW (2019) A general dual-templating approach to biomass-derived hierarchically porous heteroatom-doped carbon materials for enhanced electrocatalytic oxygen reduction