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In addition to the mevalonate pathway, statins could directly depress the AKT signal, effect the synthesis and degradation p21 and p27, at last block the cell cycle progression

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Interestingly, cavefish exhibited 80% reduction in their sleep compared to surface-dwelling populations, thus becoming a robust model for understanding evolutionary changes in sleep (Jaggard et al

[ref] Related article: GST Enzymes and Glutathione for Environmental Toxins UGT1A family and estrogenic mycotoxins (zearalenone, ochratoxin A): UGT1A1, UGT1A3, and UGT1A8 enzymes glucuronidate zearalenone, reducing its estrogenic activity and promoting excretion from the body