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Its relevance here comes from a 2018 murine study in which intranasal Semax at 0.5 mg/kg daily decreased LPS-induced serum TNF- and IL-1 by 45 to 50% and restored tight junction protein expression (claudin-2, occludin) over a 14-day intestinal inflammation model

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Commonly, a neurotransmitter is considered to be a signaling molecule secreted by a neuron to affect another cell across a synapse [12,13,14]

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