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Effect of lipoic acid consumption on oxidative stress among multiple sclerosis patients: a randomized controlled clinical trial

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Specifically, it downregulates genes and pathways related to DNA damage, OS, inflammation, and PANoptosis, while concurrently upregulating genes and signaling pathways associated with cell survival, including autophagy and mitophagy

A.WangC.BurmanJ

The 12mg weekly arm produced a 24.2% mean body weight reduction over 48 weeks, with 26% of participants achieving at least 30% total body weight loss a threshold previously unattained by any pharmacological intervention in a clinical trial setting