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While research is still developing, several groups may find it worthwhile at doses considered safe (2g or less per day): People with liver concerns Clinical studies show TUDCA can improve liver enzyme markers and bile flow in conditions like NAFLD and PBC.4 31 Benefits seem strongest in people who already have elevated enzymes or bile duct issues, rather than in generally healthy adults

However, this therapy is not indicated for men with age-related declines in testosterone alone, and its safety and efficacy have not been established for so-called late-onset hypogonadism in older males

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