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Escherichia coli Nissle 1917 protects intestinal barrier function by inhibiting NF-B-mediated activation of the MLCK-P-MLC signaling pathway

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Translating these concepts into effective therapies will require careful attention to timing, celltype specificity, combination with antiinfective and antiinflammatory measures, reliable biomarkers of ferroptotic activity, and rigorous preclinical and clinical validation

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