Several risk factors including age, hypertension, ischemic heart disease, diabetes, and chronic respiratory disease (Khanfar and Al Qaroot, 2020) increase the fatality rate (Ruan et al., 2020
Large induction of keratinocyte growth factor expression in the dermis during wound healing
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Recent investigations have also indicated AKGs potential to support tissue repair and reduce toxin-induced cellular damage, making it a valuable addition to detoxification formulas (Iqbal et al., 2021)
This design preserves long-term plasma exposure and steady-state signaling thresholds without requiring continuous infusion protocols