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It increases mitochondrial mtDNA copy number, decreases the fraction of oocytes with spindle aberrations and blastocysts from fertilized oocytes that were treated with melatonin are of higher quality

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Mercury concentrations in both serum and lung tissue were measured using atomic absorption spectroscopy (Perkin Elmer, Artisan Technology Group, USA)

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Copper ion load from AHK-Cu remains well below toxic thresholds even at 2mg daily, but chronic use beyond 6 months lacks human safety data as of 2026