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Clinical trial in hydrogel efficacy The aim of this section is to examine the current clinical-trial evidence for hydrogel applications in gynecologic oncology (particularly cervical cancer), to benchmark this against other tumor sites where hydrogels have matured clinically, and to outline how future trials should be designed to robustly demonstrate an expanded therapeutic window via hydrogel use

NAC provides a precursor to glutathione, while vitamin B6 as P5P supports enzymatic activity involved in normal detoxification and cellular metabolism

increased expression of TNF- and IL-6 in liver tissue

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This implies the existence of a GSH-dependent process that is more important for MZB than for FoB