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HFD impairs liver glutathione biosynthesis, vitamin D metabolism genes and genes associated with non-alcoholic fatty liver disease (NAFLD) Genes involved in the GSH biosynthesis pathway were significantly downregulated in the livers of mice fed an HFD compared to those of mice fed a healthy diet (controls) (Fig

A companion methodological paper in Pflgers Archiv reported the comparative properties of natural and synthetic material and the activity of metabolic fragments and analogues (Schoenenberger et al., 1977)

Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer's disease mouse model

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Pre-clinical studies showed positive neuroprotective effect of GSNO in animal stroke models [33]