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"In those with higher IGF-1 [coupled with] poorer health outcomes, this raises the question of what comes first, the elevated IGF-1 level, or a disease state-causing IGF to elevate via a different mechanism," Dr

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Rahbar MH, Samms-Vaughan M, Lee M, Zhang J, Hessabi M, Bressler J, Bach MA, Grove ML, Shakespeare-Pellington S, Beecher C, McLaughlin W, Loveland KA (2020) Interaction between a mixture of heavy metals (lead, mercury, arsenic, cadmium, manganese, aluminum) and GSTP1, GSTT1, and GSTM1 in relation to autism spectrum disorder

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