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This is a manifestation of the ongoing cercaria-schistosomulum transformation during which the old membrane is discarded in the form of small microvilli [85, 86]

Causes: The main cause of carpal tunnel syndrome is repetitive hand movements or activities that put pressure on the median nerve

Supplementary material The Supplementary Material for this article can be found online at: References 1 AbdelzaherW

via inhibiting Keap1, upregulating Nrf2 and inducing the nuclear translocation of Nrf2 ( via Sirtuin-1-Nrf2-ARE signaling pathway ( via Nrf2 to ameliorate mitochondrial oxidative stress, and further restore the activities of renal mitochondrial respiratory enzyme in various kidney diseases (Trujillo et al., 2013

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