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The rd1 mouse is a common animal model used to study RP in which the expression of over 60 genes, related to proliferation, apoptosis, and transcription, is modified via a mutation in the phosphodiesterase-6 gene, which affects the metabolism of cyclic guanosine monophosphate

Bioavailability refers to the proportion of a nutrient that is absorbed and utilized by the body

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Unlike Cdc42, Rac1 binds and activates WAVE through an adaptor protein, IRSp53, a substrate for the insulin receptor