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c-MET pathway acts on several downstream effectors including phospholipase C gamma (PLC), cellular Src kinase (c-Src), phosphotidylinsitol-3-OH kinase (PI3K), alpha serine/threonine-protein kinase (Akt), mitogen-activated protein kinase (MAPK), and wingless-related integration site (Wnt) pathways

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Cell 91 , 325334 (1997)

Researchers observed that intra-articular administration was associated with changes in cartilage matrix composition and chondrocyte activity markers in the treated joints compared to controls [3]

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