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doi: 10.1016/j.jaci.2009.10.031

These PL-PUFAs are then oxidized by iron-dependent enzymes as lipoxygenases (LOXs) or the labile iron pool into lipid hydroperoxides (PL-PUFA-OOH) to undergo the Fenton reaction under the presence of ferrous iron to trigger ferroptosis onset (Xl et al., 2022)

There's a specific gene called MC1R that's linked to red hair, fair skin, and a tendency to freckle easily

The majority of Chinese participants were male (80.0%), while the proportions of male and female Caucasian participants were roughly equal (53.3% and 46.7%, respectively) (Table 1)