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High exposure to polyaromatic hydrocarbons in the womb has been associated with lower IQ and childhood asthma, as well as adverse post-birth effects including heart malformations and DNA damage

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The FDA should consider public education and communication about the purpose of FDA authorization, including the potential benefits of switching to these products for those who smoke and the potential harms of using e-cigarettes for those who do not use tobacco

They also examined 20 HIV-positive smokers who completely switched from tobacco cigarettes to EC during an 8-week follow-up, demonstrating clinical improvement in symptoms such as coughing, wheezing, and shortness of breath, a decrease in daily cigarette consumption, and complete cessation in seven participants (51)