penetration-enhanced preparations (including palmitoylated versions such as Pal-GHK) are needed for meaningful dermal delivery Injectable advantages: bypasses the skin barrier entirely, delivers GHK-Cu systemically, and can be combined in the same protocol as BPC-157 and TB-500 for comprehensive wound care The distinction between topical and injectable GHK-Cu is clinically important and is not simply a matter of convenience
doi:10.1111/j.1749-6632.1975.tb25349.x
When it crosses the blood-brain barrier and binds to c-Met, it initiates synaptogenesis: new dendritic spines form, synaptic connections strengthen, and neurons that were alive but under-connected begin to integrate more fully into functional networks
Zamani M, Zarei M, Nikbaf-Shandiz M, Hosseini S, Shiraseb F, Asbaghi O
Medically reviewed by Richard Dentico, MD