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NRF-2 has six Neh domains

While their full MoA remains to be elucidated, it is known that they can activate Nrf2

Environmental factors such as pollution, UV exposure, stress, and lifestyle habits can increase oxidative stress levels, which is why antioxidants are an important area of interest in skin health

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Studying Enzyme Function and Regulation Analyzing the metabolites involved in the PPP can provide insights into the function and regulation of key enzymes such as G6PD, 6-phosphogluconate dehydrogenase, and transketolase