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Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

The researchers highlighted silymarin's liver-protective effects in cases of drug-induced liver injury, fatty liver disease (both alcoholic and nonalcoholic), and alcoholic cirrhosis, attributing successes to the compound's ability to prevent cytotoxicity by reducing oxidative stress on the liver.3 Many of the studies covered in the review administered 420mg of silymarin per day

doi: 10.1038/sj.pcan.4500550 101 MaistroSSnitcovskyISarkisASda SilvaIABrentaniMM