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in the collection, analyses, or interpretation of data

Furthermore, in some tumours, the need for methyl groups for epigenetic regulation prevents activation of the trans-sulphuration pathway for cysteine synthesis, instead prioritising one-carbon metabolism

Similarly, the same decrease in GSH and increase in MDA after knockdown of HO-1 was observed under the RSL3 ferroptosis model

Altogether, these studies indicate that chronic ethanol intake affects the mitochondrial structure and function, promoting the ROS production, altering substrate transport through the mitochondrial membrane, expression of the electron transport chain complex I and V, and ATP synthesis [24]

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