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Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs Summary: This preclinical study investigated the pharmacokinetics of BPC 157 in rats and dogs

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Furthermore, the crystal structure of human serine hydroxymethyltransferase (hSHMT1/2) interacting with endogenous glycine-conjugated secondary bile acids, combined with mutational analysis, biophysical measurements, and structure-activity relationship studies, demonstrates specific interactions between hSHMT and its ligands, suggesting that secondary bile acid conjugates might function as modulators of SHMT activity [128]

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