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Periarticular injection (near but not into the joint) near the shoulder injury site may produce faster localized effects than distant subcutaneous injection

Chem Bio Chem 16, 14901496 (2015)

In our experiments, exogenous rapamycin significantly decreased the proportion of SA--Gal-positive cells and p16 expression, whereas autophagy inhibitors 3-MA and Baf-A1 produced opposite effects

Torino F, Barnabei A, Paragliola R, Baldelli R, Appetecchia M, Corsello SM

HUBERMAN: They'll take this by, typically it's an injection that's given subcutaneously at night, and they achieve growth of tissues, including muscle, et cetera