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The enrichment of genes associated with regional emphysema severity with COPD-related phenotypes in these other datasets suggests that the biological processes associated with increasing emphysema severity within a patient with severe COPD also vary in individuals with earlier stages of disease

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When these levels drop, our cells become more vulnerable to damage, which can lead to feelings of fatigue, brain fog, and a less responsive immune system

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Covering each is out-of-scope for this article, so well instead highlight just two