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In very hyperkeratotic disease, ablative laser (laser-assisted drug delivery) may help in reducing hyperkeratosis and facilitating corticosteroid absorption, but must be used in conjunction with a topical corticosteroid

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Compared with the control group, the proportion of EPCs in G1/S phase in the CTPB group is higher, indicating that CTPB may prevent EPCs from entering S phase from G1 phase by increasing the relative expression of p300 protein