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Until the early 1920s, cigarettes were still not the dominant tobacco product and were considered the lot of the poor in many countries

This chapter reviews the current knowledge on different mechanisms through which both direct and secondhand CS-induced oxidative stress in lungs plays a significant role in the pathogenesis of COPD

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Volatile organic compounds (VOC), polycyclic aromatic hydrocarbons (PAH) and carbon monoxide (CO) were present in the smoke from the IQOS , summarises the article in the journal JAMA Internal Medicine