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Put another way, if the tertiary structures of two molecules (or supramolecular aggregates) resemble each other closely enough to fool an antibody into cross-reacting, then by the same token such a similarity could prompt an endogenous brain protein into being cross-seeded and templated by an exogenous prion-like element

Some important terms to understand: Free Radical a molecule with an unpaired electron in its outer orbital

EpCAM signaling is activated when EpCAM is cleaved into EpEX and intracellular domain (EpICD) by specific enzymes

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Lower complement C1q levels in first-episode psychosis and in schizophrenia