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Therefore, harmine appears to have greater potential as a chemosensitizing agent in cancer cells exhibiting multidrug resistance phenotypes

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From the early epidemiology work of Richard Doll and Austin Bradford Hill, the reports from the Surgeon General and the Royal College of Physicians, the link between cigarette smoking and lung cancer acquired full scientific consensus already in the late 1970s, which arose the attention of the public and the medical establishment, not only in the US, but also in the anglosphere and then globally, leading to the FTCT, the first international treaty on a health issue, sponsored by the WHO and signed by 158 countries