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10.1016/j.copbio.2012.08.005 34 McGuireS

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doi: 10.1038/s41598-022-19040-8 2 AbrunhosaL.PatersonR

In clinical trials, discontinuation of Tesamorelin resulted in a return of visceral fat toward baseline levels over 36 months, suggesting ongoing use may be needed to maintain body composition benefits

The reason for the difference is that when folic acid is added to food or taken as a dietary supplement with food it is at least 85% absorbed, whereas only about 50% of folate naturally present in food is absorbed