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In addition, the exposed cell lines showed a higher expression of H2A histone family member X (-H2AX), a well-defined marker for double-strand DNA breaks

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Why This Study Matters Cannabis smoke contains known carcinogens, including benzopyrene, benzanthracene, and fine particulate matter, and prior research has suggested that smoking cannabis may induce bronchial molecular and histopathologic changes linked to carcinogenesis (Pradre et al., 2026)

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