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KEGG pathway enrichment analysis showed that NFAT5 may participate in the regulation of macrophage inflammatory response through NIK/ NF-B2 signalinga non-canonical pathway involving p100 precursor processing into transcriptionally active p52/RelB dimers that mediate immune regulation and inflammation [54,55,56]

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SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53