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Since the days of SURMOUNT-5 when LLY compared its Tirzepatide to NVOs Semaglutide a further head-to-head has been on the cards and NVO took it upon themselves to face off its next weight-loss asset, CagriSema against Tirzepatide

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However, mechanistic plausibility does not establish clinical benefit, and the current evidence base does not support claims of improved healing, accelerated recovery, or reduced complication rates following orthopaedic surgery