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You cannot simply take your oral daily dose, multiply by seven, and use that as your weekly injectable dose

Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8

We generally say having seven or eight fillings is a problem that needs to be addressed (by a specialized Dentist) after getting the patients general health under control

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Individuals with Lebers disease: A rare genetic condition that primarily affects the optic nerve, Lebers disease becomes more serious in people who take vitamin B12 supplements