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Free radicals can arise from normal cell function or enter the body through environmental factors such as stress, smoking, alcohol consumption, polluted air, and ultraviolet (UV) radiation

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Transfection HEK-293T cells were cultured in 100-mm dishes and transfected upon 70% confluency

However, DSIP has delayed effects, with some research administering doses hours before bed or even during the day with benefits extending to that night's sleep