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Description

Int J Clin Pharmacol.Ther Toxicol

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In SH-SY5Y cells stimulated with A 142 or 6-OHDA, DMF has been reported to increase cellular viability and reduce intracellular ROS production, both through the activation of HMOX-1, while a study treating ALS patient-derived macrophages demonstrated DMFs ability to inhibit pro-inflammatory cytokines as well as NF-kB (Table 1)

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Of course, there are also environmental and lifestyle factors at play

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AD pathophysiology involves a dysregulated immune response driven by T helper-2 cells

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