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These effects were dependent on the integrity of synaptic transmission as they were blocked by tetrodotoxin (TTX)

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Pre-Treatment Guidelines - Avoid alcohol and excessive fatty meals before PT-141 administration to prevent nausea.- Avoid eating 2 hours before and after Sermorelin to enhance GH response.- Store injectable peptides and NAD+ in the refrigerator after reconstitution.- Monitor blood pressure regularly if using PT-141

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The supernatant was collected and stored on ice, when used immediately, or frozen at 80 C for future use

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