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Inset: wells of the 96-well microplate are numbered following a horizontal zig-zag pattern from A1 (well number 1)

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In conclusion, the results of this study not only further verified that FRP in AD treatment has the characteristics of multiple components, multiple targets, and multiple pathways through network pharmacology but also identified possible leading compounds with potential multi anti-AD activity

In addition, NR protected against the detrimental metabolic effects of a high-fat diet, including hyperinsulinemia, elevated levels of total and LDL cholesterol, and weight gain, although it had no effect on body weight when given with a normal chow diet [95]

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