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Again, though, these actions are largely characterized in cell and animal systems, and their relevance to visible human skin change depends entirely on whether an effective concentration reaches the dermis by the route in question

J Exp Bot 60:17431757 Coleman ST, Fang TK, Rovinsky SA, Turano FJ, Moye- Rowley WS (2001) Expression of a glutamate decarboxylase homologue is required for normal oxidative stress tolerance in Saccharomyces cerevisiae

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