Evidence for loading protocols remains anecdotal, and many users achieve good results with consistent moderate dosing from day one
[7] In practice, some protocols use 1 mg IM monthly for maintenance once levels are stabilized
Consider your experience level Beginners (never used peptides): Start with safest, most forgiving peptides BPC-157, collagen peptides, basic GH peptides Avoid aggressive or complex protocols Intermediate (used 1-3 peptides): Can try more potent options Stack 2-3 peptides safely Understand dosing and cycles Advanced (extensive peptide experience): Can use powerful peptides (IGF-1, aggressive GH protocols) Complex stacks Self-monitor and adjust See our getting started with peptides guide and common peptide mistakes beginners make
Excessive NNMT in the body is associated with aging and age-related diseases, as well as disruptions to systems that regulate metabolism and weight
The original 2015 Cell Metabolism study demonstrated that intraperitoneal MOTS-c injections (5 mg/kg) in mice fed a high-fat diet prevented obesity and insulin resistance, with effects on fat mass, fasting glucose, and insulin sensitivity that rivaled pharmaceutical intervention [1]
