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doi: 10.1038/nrc2444 35 RiveraLBBergersG

[24] [10] [25] Four trials were conducted in ED, the last being a Phase IIb published in 2008

Tumor-associated fibroblasts amplify oxidative stress in surrounding monocytes, promoting their differentiation into MDSCs, which in turn inhibit CD8+ T cell proliferation (104)

Elevated concentrations of GABA in the cerebrospinal fluid of women with PCOS, GABA seems to exert an excitatory effect on GnRH neurons and this leads to greater secretion of LH by the pituitary gland, as occurs in PCOS [18, 19]