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Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum

It stimulates the synthesis of key ECM components, including collagen I and III, elastin, and various glycosaminoglycans (GAGs), by signaling through pathways such as the TGF-/SMAD cascade

The compound also enhances GLUT4 expression and promotes production of palmitic acid hydroxy stearic acids (PAHSAs), an alternative lipid class exhibiting anti-diabetic and anti-inflammatory properties