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However, it increased heart rate, cardiac output, and induced myocardial degeneration in mice and thus was terminated as a preclinical candidate ( Inhibitors of c-Met Downstream Mediators To solve the side effects mentioned above, several therapy strategies have been suggested

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[DOI] [PubMed] [Google Scholar] 214.Fedacko J., Pella D., Fedackova P., Hnninen O., Tuomainen P., Jarcuska P., Lopuchovsky T., Jedlickova L., Merkovska L., Littarru G.P

J., Finkelman, F