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We find that the binding site of both compounds is identical to that for a similar molecule that remains naturally attached to the virus 7 , and to the binding site observed for the benzene-sulfonamide derivative in complex with Coxsackievirus B3 8 , identifying the biological role for this binding site

Although further clinical evidences are still needed for elucidating the precise mechanism, it is considered plausible that EAAC1 dysfunction leading to GSH depletion is closely involved in neurodegenerative diseases

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