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Chondrocytes within the soft callus undergo programmed cell death, leaving behind a calcified cartilage matrix

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It is tempting to speculate that a previously described internal promoter of yet unknown function may play a role in adjusting and fine tuning of the independent transcription of cesA and cesB, thereby decoupling CesA and CesB to a certain extend 11

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When converted to hydroxyl, hydrogen peroxide is able to cross membranes, and ozone is a powerful oxidant of lipid chains, as well as it is able to interact with different organic and inorganic substances, in addition to generating other free radicals (Bensakhria 2018)