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AAM, BJP, and AS performed literature searches and selected the studies and reviews discussed in the manuscript
Variable protein expression in platelets found evidence that the delE155 enzyme is present in platelets obtained from subjects that are heterozygous for the GSTO1delE155, K208 allele E173K site-directed mutagenesis of isozyme GST T1-1, the mutant shows reduced expression levels and enzyme activity with all substrates compared to the wild-type enzyme
Abstract It has remained unknown how cells reduce cystine taken up from the extracellular space, which is a required step for further utilization of cysteine in key processes such as protein or glutathione synthesis
Wilson disease is present at birth (congenital), but the symptoms dont appear until copper builds up in your liver, brain, eyes or other organs
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