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This decrease in DHEA and initial rise in cortisol leads to an elevated cortisol/DHEA ratio, which in turn leads to very harmful consequences such as (2): Lower insulin sensitivity with increased blood sugar leading to diabetes

Conclusion This review highlights the potential role of alogliptin and mechanisms involved in amelioration of several other pathological conditions apart from its role in glucose metabolism

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Pregnancy and breastfeeding require avoiding both compounds entirely

The FDA has approved semaglutide under two brand names: Ozempic for type 2 diabetes management and Wegovy for chronic weight management